Here’s a look at the companies with the biggest gainers at noon: Inspire Medical Systems, ResMed — Inspire Medical Systems and ResMed, which make devices to treat obstructive sleep apnea, were down 14% and 11%, respectively, on Friday’s news that Eli Lilly was losing weight. The drug tezepatide reduced the severity of the condition. Eli Lilly also said it has applied to the U.S. Food and Drug Administration for approval of the drug to treat sleep apnea. Eli Lilly shares rose 2%. RXO — Shares of RXO rose 23% after the trucking company said it has reached an agreement to acquire Coyote Logistics from UPS for more than $1 billion. UPS rose 1.5%. Alnylam Pharmaceuticals — The clinical-stage therapeutics company soared 37% after a Phase 3 study found its drug vutrisiran statistically significantly reduced the number of deaths and cardiovascular events in patients with ATTR amyloid cardiomyopathy. Nvidia — Shares fell nearly 5%. Nvidia shares have fallen recently after falling 4% last week, snapping an eight-week winning streak. Last week, the artificial intelligence darling briefly overtook Microsoft as the most valuable company in the United States. Confirmation – The stock rose 10% after Goldman Sachs issued a buy rating on the company. Analyst Will Nance cited the stock’s strong fundamentals, including its differentiated approach to credit underwriting, as a catalyst for the name. Cinemamark – Shares of the movie theater chain rose more than 5%. Ross MKM upgraded Cinemark to buy from neutral and said the headwinds should soon turn into “very attractive tailwinds.” The company also cited “meaningful box office improvements.” Anheuser-Busch InBev — Shares of the beer company rose about 3% after UBS upgraded the stock to buy from neutral. The bank noted that Anheuser-Busch is “on the cusp of achieving a desirable consumer staples growth profile,” citing inflection points in growth, margins and cash returns. IBM – The stock soared nearly 3% after Goldman Sachs initiated a buy rating and set a $200 price target, implying a 16% upside from Friday’s closing price. The legacy technology company expects to maintain long-term revenue and free cash flow growth, driven by growth in artificial intelligence products and services, growth in consulting market share and growth in its core software portfolio, the company said. Ryder System — Shares of the trucking company rose nearly 3% after Morgan Stanley initiated an overweight rating. The company cited cyclical inflection points, regulatory changes and secular outsourcing tailwinds as catalysts. Carrier Global — Heating and ventilation stocks rose 3% after Citi upgraded the stock to “buy” from “neutral.” Citi said the company could become an alternative pure-play HVAC provider with an improving price-to-earnings ratio after the end of its business transformation program. Planet Fitness — The health club franchise gained about 1% after TD Cowen upgraded the stock to buy. The firm also named Planet Fitness as a top pick, calling the stock an early turnaround stock. UBS raised its target price on Ferrari to $478 from $448, sending the luxury carmaker’s shares up nearly 2% and up 15% from Friday’s closing price. Ferrari unveiled a new electric car factory last week. ENERGY STOCK – A range of energy stocks rose as crude oil futures began to rise in the last week of June. West Texas Intermediate crude oil futures and Brent crude oil futures both rose by more than 5% on the month. SLB, APA and Baker Hughes all gained more than 3% on Monday. —CNBC’s Lisa Han, Jesse Pound, Alex Harring, Sean Conlon and Samantha Subin contributed reporting.